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Published on: August 1, 2018
Thiol-yne Click Post-Modification for the Synthesis of Chiral Microporous Organic Networks for Chiral Gas
Yuan-Yuan Cui1, Cheng-Xiong Yang1, Xiu-Ping Yan2
1College of Chemistry, Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition , Nankai University , Tianjin 300071 , China.
Abstract:
Microporous organic networks (MONs) have shown great potential in diverse domains recently. However, the application of MONs in chiral separation or catalysis has been largely lagged due to the lack of chiral MONs and the challenge to synthesize chiral MONs. Here we report a facile thiol-yne click strategy to post-synthesize chiral MONs for the first application in chiral gas chromatography. Three chiral MONs with different chiral centers were rationally designed and synthesized to fabricate their capillary columns for gas chromatographic resolution of various chiral compounds with better resolution than three commercial chiral capillary columns. These results show the great potential of the thiol-yne click strategy for constructing newly chiral MONs and their application in chiral separation.
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