Related Experiment Video
Updated: Dec 31, 2025

08:18
Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
570
Longitudinal Changes in Adult Bony Orbital Volume
Brian Chon1, Kevin R Zhang2, Catherine J Hwang1
1Cole Eye Institute, Cleveland Clinic, Department of Ophthalmology.
Ophthalmic Plastic and Reconstructive Surgery
|January 3, 2020
Summary
Bony orbital volume significantly increases with age, by approximately 4.1%. This age-related change in orbital bone volume contributes to the aging appearance of the periorbital region.
Area of Science:
- Anatomy
- Aging Research
- Medical Imaging
Background:
- Longitudinal studies on bony orbital volume changes over time are lacking.
- Understanding age-related anatomical changes is crucial for periorbital aesthetics and reconstructive surgery.
Purpose of the Study:
- To measure longitudinal changes in bony orbital volume.
- To evaluate the relationship between aging and bony orbital volume.
Main Methods:
- Retrospective analysis of CT scans from 182 subjects with scans at least 8 years apart.
- Exclusion of subjects with conditions affecting bone metabolism or orbital structures.
- Measurement of orbital volume, medial orbital wall length, and lateral orbital wall length.
Main Results:
- Bony orbital volume significantly increased by 4.1% (0.91 ml) over approximately 9.4 years (p < 0.001).
- Lateral orbital wall length decreased slightly (0.4 mm, p = 0.046).
- No significant change was observed in medial orbital wall length.
Conclusions:
- Bony orbital volume increases with age.
- This volumetric increase, alongside soft tissue changes, contributes to the aging periorbital appearance.
More Related Videos
Related Concept Videos
Changes in the Appendicular Skeleton with Age
3.3K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.3K
Cranial Bones: Lateral View
4.3K
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
4.3K
Accessory Structures of the Eye
3.2K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
3.2K
Sutures of the Skull
9.9K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
9.9K
Growth of Cartilage and Bone Tissue
3.9K
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
3.9K
Bone Formation by Intramembranous Ossification
9.8K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
9.8K

