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OPTN/SRTR 2018 Annual Data Report: Pancreas.

R Kandaswamy1,2, P G Stock3, S K Gustafson1

  • 1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|January 4, 2020
PubMed
Summary

Pancreas transplants are increasing, with more type II diabetes patients receiving them. Waiting times have decreased, and patient outcomes, including survival and rejection rates, are improving.

Keywords:
Pancreas transplantpancreas after kidney transplantpancreas transplant alonesimultaneous kidney pancreas transplant

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Area of Science:

  • Transplantation Medicine
  • Endocrinology
  • Nephrology

Background:

  • Pancreas transplantation is a vital treatment for end-stage organ failure.
  • The prevalence of type II diabetes is increasing, impacting transplant candidate demographics.

Purpose of the Study:

  • To analyze trends in pancreas transplantation, including waiting list dynamics, patient demographics, and transplant outcomes.
  • To assess changes in waiting times and survival rates for pancreas and simultaneous pancreas/kidney transplants.

Main Methods:

  • Analysis of national transplant registry data from the Organ Procurement and Transplantation Network (OPTN).
  • Examination of trends from 2015 to 2018, focusing on patient demographics, waiting times, and survival outcomes.

Main Results:

  • Overall pancreas transplants increased to 1027 in 2018, rising from a 2015 low.
  • Proportion of type II diabetes patients on waiting lists and undergoing transplant has increased.
  • Waiting times for simultaneous pancreas/kidney transplant decreased to a median of 13.5 months.
  • Patient and kidney survival rates have improved, with decreasing rejection rates.

Conclusions:

  • Pancreas transplantation numbers are rising, with a notable increase in type II diabetes recipients.
  • Improved outcomes in patient and kidney survival, alongside reduced rejection rates, indicate advancements in transplant care.
  • Decreased waiting times for simultaneous pancreas/kidney transplants suggest improved efficiency in the transplant process.