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Author Spotlight: Enhancing Skin Model Diversity with Cost-Effective 3D Cellular Models
Published on: October 20, 2023
Skin Health from the Inside Out
Brittany Woodby1, Kayla Penta1, Alessandra Pecorelli1
1Plants for Human Health Institute, Department of Animal Science, North Carolina State University, Kannapolis, North Carolina 28081, USA;
This review explores how antioxidants combat skin aging caused by environmental stressors. Combining topical and dietary antioxidants, plus probiotics and minerals, protects skin from damage and premature aging.
Area of Science:
- Dermatology and Environmental Science
- Biochemistry of Skin Aging
Background:
- The skin acts as a barrier against environmental pollutants like UV light and ozone.
- Exposure to these stressors generates reactive oxygen species (ROS), overwhelming natural defenses.
- This oxidative stress leads to premature skin aging, DNA damage, and inflammation.
Purpose of the Study:
- To review strategies for protecting the skin against environmental stressors.
- To discuss the role of antioxidants in mitigating oxidative stress and skin aging.
Main Methods:
- Literature review of studies on antioxidants and skin protection.
- Analysis of topical and dietary antioxidant strategies.
- Inclusion of probiotics and essential minerals in the protective approach.
Main Results:
- Topical antioxidants (Vitamins C, E, carotenoids, resveratrol, pycnogenol) show protective effects.
- Dietary supplementation with antioxidants, probiotics, and minerals enhances skin defense.
- Combined approaches offer comprehensive protection against aging factors.
Conclusions:
- Antioxidant therapies, both topical and dietary, are effective against environmental skin damage.
- A holistic approach combining antioxidants, probiotics, and minerals offers superior protection.
- These strategies can prevent premature skin aging induced by oxidative stress.
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