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A Long-Term Follow-up of Retinal Vasculitis - Do They Develop Systemic Disease?
Ankush Kawali1, Bharathi Bavaharan2, Srinivasan Sanjay1
1Department of Uveitis and Ocular Immunology, Narayana Nethralaya , Bangalore, India.
Ocular Immunology and Inflammation
|January 8, 2020
Summary
Systemic associations rarely develop in primary retinal vasculitis (PRV) and possible tubercular vasculitis (PTV) patients during long-term follow-up. Relapse rates were similar between PRV and PTV cases.
Area of Science:
- Ophthalmology
- Rheumatology
- Infectious Diseases
Background:
- Primary retinal vasculitis (PRV) and possible tubercular vasculitis (PTV) are inflammatory conditions affecting the eye's blood vessels.
- Understanding long-term outcomes, including systemic associations and relapse patterns, is crucial for patient management.
Purpose of the Study:
- To investigate systemic associations in patients with PRV and PTV.
- To analyze relapse rates and patterns in a long-term follow-up cohort of PRV and PTV patients.
Main Methods:
- Retrospective, descriptive chart review of patients diagnosed with PRV or PTV.
- Inclusion criteria required a minimum of 1-year follow-up.
- Data collected included clinical presentation, systemic associations, vasculitis morphology, relapse occurrences, and treatment strategies.
Main Results:
- The study analyzed 123 eyes from 76 patients.
- Occlusive vasculitis was the most common type (n=97).
- Vitreous hemorrhage occurred in 27% of eyes at presentation.
- Four patients (3.25%) developed systemic diseases (psoriasis, SLE, ulcerative colitis) during follow-up.
- Relapse rates were high and similar in both PRV (66.66%) and PTV (66.66%) groups (p=1).
Conclusions:
- Systemic disease development is rare but possible in long-term PRV and PTV follow-up.
- Relapse frequencies are comparable between PRV and PTV, indicating similar disease behavior regarding recurrence.
