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Tinea Capitis: An Updated Review.

Alexander K C Leung¹, Kam L Hon², Kin F Leong³

¹Department of Pediatrics, The University of Calgary, Alberta Children's Hospital, Calgary, Alberta, Canada.

Recent Patents on Inflammation & Allergy Drug Discovery

|January 8, 2020

Summary

This summary is machine-generated.

Tinea capitis, a common fungal scalp infection, requires systemic antifungal treatment for effective management. Combined topical and oral antifungal therapies may improve cure rates and reduce spore transmission.

Keywords:

Alopecia black dots dermatophytes favus fluconazole griseofulvin itraconazole kerion terbinafine.

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Area of Science:

Dermatology
Mycology
Infectious Diseases

Background:

Tinea capitis is a prevalent and often challenging fungal infection affecting the scalp.
It commonly impacts children between 3 and 7 years of age.

Purpose of the Study:

To provide an updated overview of the evaluation, diagnosis, and treatment of tinea capitis.
To discuss recent advancements and therapeutic strategies for this condition.

Main Methods:

A comprehensive literature search was conducted using PubMed, focusing on tinea capitis.
Included study types were meta-analyses, RCTs, clinical trials, observational studies, and reviews in English.
Patent literature was also reviewed for relevant management strategies.

Main Results:

Tinea capitis is primarily caused by Trichophyton tonsurans and Microsporum canis.
Clinical presentations range from non-inflammatory scaling and alopecia to inflammatory forms like kerion and favus.
Dermoscopy, KOH wet mounts, and fungal cultures are key diagnostic tools; mycologic confirmation is recommended before treatment.

Conclusions:

Systemic antifungal therapy is essential for treating tinea capitis due to deep-seated infections.
Topical antifungals alone are insufficient but can be used adjunctively to reduce transmission and enhance systemic treatment efficacy.
Combination therapy with oral and topical antifungals shows promise for increasing cure rates.