[Research progress in the application of intralymphatic allergen immunotherapy in allergic diseases]

SummaryAlthough subcutaneous immunotherapy （SCIT） and sublingual immunotherapy （SLIT） have a positive effect, there are drawbacks such as long treatment time period, frequent treatment times, and risk of adverse reactions. Peripheral superficial lymph node injection of allergen immunotherapy （ILIT） as an emerging specific immunotherapy method has the advantages of high safety, less adverse reactions, short treatment time, less treatment times, less patient pain, and exact curative effect. In recent years, more and more scholars have conducted extensive research on intra-lymphatic injection of immunotherapy for allergic diseases. This paper systematically summarizes the theoretical basis, method, safety, effectiveness and possible immune mechanism of ILIT.