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Related Concept Videos

Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

5.6K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
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Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

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Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
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Feedback Regulation of Calcium Concentration01:27

Feedback Regulation of Calcium Concentration

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Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...
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Roles of Electrolytes: Calcium and Phosphate01:27

Roles of Electrolytes: Calcium and Phosphate

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Calcium and phosphate are essential electrolytes in the human body, with calcium being the most abundant mineral. Around 99% of the body's calcium is stored in the skeleton and teeth, forming a crystal lattice of mineral salts in combination with phosphates. Calcium plays crucial roles in various bodily functions such as blood clotting, neurotransmitter release, muscle tone maintenance, and nervous and muscle tissue excitability.
The calcium concentration in blood plasma is primarily...
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Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

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Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
209
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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Related Experiment Video

Updated: Dec 31, 2025

Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates
05:58

Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates

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Calcium Levels in the Neonate.

Jeanne M Perino

    Neonatal Network : NN
    |January 11, 2020
    PubMed
    Summary

    Neonatal calcium levels are crucial for development and regulated by hormones. Careful monitoring is essential to prevent serious complications affecting the nervous, cardiac, and musculoskeletal systems.

    Area of Science:

    • Biochemistry
    • Neonatal Physiology
    • Endocrinology

    Background:

    • Calcium is the most abundant ion in neonates.
    • It is vital for bone formation, blood coagulation, muscle contractility, and nerve conduction.
    • Hormonal regulation involves parathyroid hormone, calcitonin, and vitamin D via negative feedback.

    Purpose of the Study:

    • To highlight the importance of calcium in neonatal physiology.
    • To emphasize the regulatory mechanisms of calcium homeostasis.
    • To underscore the necessity of monitoring neonatal calcium levels.

    Main Methods:

    • Review of existing literature on neonatal calcium metabolism.
    • Analysis of the roles of key hormones in calcium regulation.
    • Discussion of potential complications associated with calcium imbalances.
    Keywords:
    metabolicneonatal hypocalcemiaparathyroid hormone

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    Transcutaneous Microcirculatory Imaging in Preterm Neonates
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    Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis
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    Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis

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    Related Experiment Videos

    Last Updated: Dec 31, 2025

    Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates
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    Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates

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    Transcutaneous Microcirculatory Imaging in Preterm Neonates
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    Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis
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    Main Results:

    • Calcium's multifaceted role in neonatal development confirmed.
    • Negative feedback loop involving parathyroid hormone, calcitonin, and vitamin D elucidated.
    • Significant risks associated with unmonitored calcium levels identified.

    Conclusions:

    • Maintaining optimal neonatal calcium levels is critical.
    • Careful monitoring is required to prevent neurological, cardiac, and musculoskeletal issues.
    • Understanding calcium homeostasis is key to neonatal care.