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Using the MINT Database to Search Protein Interactions.

Alberto Calderone1, Marta Iannuccelli1, Daniele Peluso2

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|January 17, 2020
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Summary
This summary is machine-generated.

The Molecular INTeractions Database (MINT) provides a public resource for protein interaction data curated from scientific literature. This article details how to search and utilize MINT

Keywords:
MINTdatabaseprotein-protein interaction

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Area of Science:

  • Biochemistry
  • Bioinformatics
  • Molecular Biology

Background:

  • Protein interactions are fundamental to cellular processes.
  • Accessing curated protein interaction data is crucial for biological research.
  • The Molecular INTeractions Database (MINT) serves as a public repository for such data.

Purpose of the Study:

  • To provide protocols for accessing and utilizing the Molecular INTeractions Database (MINT).
  • To introduce the new MINT Web Page for enhanced user interaction.
  • To guide users in searching and submitting protein interaction data.

Main Methods:

  • Utilizing the MINT Web Page for internet-based searching of protein interactions.
  • Employing the MINT visualizer for data exploration.
  • Following established protocols for submitting new interaction data to the database.

Main Results:

  • MINT contains extensive data on over 26,000 proteins and 131,600 interactions across multiple model organisms (as of October 2019).
  • The MINT Web Page offers user-friendly protocols for data retrieval.
  • Clear procedures are provided for data submission, contributing to the database's growth.

Conclusions:

  • The MINT database is a valuable, publicly accessible resource for protein interaction information.
  • The MINT Web Page facilitates efficient searching and data exploration.
  • User contributions through data submission are encouraged to expand the MINT knowledge base.