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Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection
Published on: October 25, 2013
Computational Evaluation of Suspended Microcantilever and Microfluidic Channel
Abstract:
In this study, a static mode suspended microcantilever model was simulated employing the Finite Elements Method (FEM), to examine the deflection of the microcantilever's beam using Newtonian and Non-Newtonian fluids. The scope of this work is to design and simulate a suspended microcantilever biosensor for the determination of the fluids' dynamic viscosity and the relationship between the blood's hematocrit and the biosensor's sensitivity. These biosensors are microstructures which consist of a microfluidic channel embedded in a microcantilever biosensor. Fluid Structure Interaction (FSI) simulations performed to study the deflection of the microcantilever when Newtonian and Non-Newtonian fluids with different dynamic viscosity are used. For the dynamic viscosity determination of the Non-Newtonian fluids, the Brid-Carreau model was used. The results indicate a proportional relation between the beam's deflection and the fluids' dynamic viscosity.

