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Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
Published on: November 15, 2024
[Gastroenterology and hepatology in 2019]
Caroline Bastid1, Pablo Gressot1, Jean-Louis Frossard1
1Service de gastroentérologie et hépatologie, HUG, 1211 Genève 14.
Insights
Key 2019 gastroenterology and hepatology updates include aspirin for NAFLD, tenofovir for HBV, and budesonide for eosinophilic esophagitis. New guidelines also address ulcerative colitis and celiac disease surveillance.
Area of Science:
- Gastroenterology
- Hepatology
- Internal Medicine
Background:
- Significant advancements in gastroenterology and hepatology occurred in 2019.
- Clinical practice guidelines and treatment protocols underwent important updates.
Purpose of the Study:
- To review the most significant innovations and updates in gastroenterology and hepatology from 2019.
- To provide a concise overview of key findings and recommendations.
Main Methods:
- Literature review of major studies and clinical trials published in 2019.
- Synthesis of findings related to various gastrointestinal and liver conditions.
Main Results:
- Ursodeoxycholic acid's role in pregnancy cholestasis is debated.
- Aspirin shows potential in preventing fibrotic non-alcoholic fatty liver disease (NAFLD).
- Tenofovir is confirmed as the standard for treating hepatitis B virus (HBV) in pregnancy.
- Carvedilol's efficacy in portal hypertension is reaffirmed.
- Increased surveillance for intraductal papillary mucinous neoplasms (TIPMP) is recommended.
- Systematic colonoscopy post-acute diverticulitis is advised.
- Celiac disease surveillance protocols are updated.
- Tofacitinib is effective for ulcerative colitis, with precautions.
- Budesonide tablets are validated for eosinophilic esophagitis.
Conclusions:
- The year 2019 brought several critical updates impacting the management of diverse gastrointestinal and hepatological conditions.
- Clinicians should be aware of these advancements for optimal patient care.
Abstract:
This article aims to review the most important innovations and updates in gastroenterology and hepatology in 2019. The role of ursodesoxycholic acid is questioned in cholestasis during pregnancy. Aspirin appears to prevent fibrotic lesions in NALFD. Tenofovir remains the gold standard in the treatment (TT) of HBV during pregnancy. The role of carvedilol is confirmed in the TT of portal hypertension. The risk of degeneration of TIPMP lesions suggests increased surveillance. Colonoscopy should be systematic after an episode of acute diverticulitis. The surveillance of celiac disease is specified. Tofacitinib is an effective molecule in ulcerative colitis but precautions are needed. Budesonide tablet is validated for the TT of eosinophilic esophagitis.
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