[Gastroenterology and hepatology in 2019]

Caroline Bastid1, Pablo Gressot1, Jean-Louis Frossard1

  • 1Service de gastroentérologie et hépatologie, HUG, 1211 Genève 14.

Revue Medicale Suisse
|January 22, 2020
PubMed

Insights

Key 2019 gastroenterology and hepatology updates include aspirin for NAFLD, tenofovir for HBV, and budesonide for eosinophilic esophagitis. New guidelines also address ulcerative colitis and celiac disease surveillance.

Area of Science:

  • Gastroenterology
  • Hepatology
  • Internal Medicine

Background:

  • Significant advancements in gastroenterology and hepatology occurred in 2019.
  • Clinical practice guidelines and treatment protocols underwent important updates.

Purpose of the Study:

  • To review the most significant innovations and updates in gastroenterology and hepatology from 2019.
  • To provide a concise overview of key findings and recommendations.

Main Methods:

  • Literature review of major studies and clinical trials published in 2019.
  • Synthesis of findings related to various gastrointestinal and liver conditions.

Main Results:

  • Ursodeoxycholic acid's role in pregnancy cholestasis is debated.
  • Aspirin shows potential in preventing fibrotic non-alcoholic fatty liver disease (NAFLD).
  • Tenofovir is confirmed as the standard for treating hepatitis B virus (HBV) in pregnancy.
  • Carvedilol's efficacy in portal hypertension is reaffirmed.
  • Increased surveillance for intraductal papillary mucinous neoplasms (TIPMP) is recommended.
  • Systematic colonoscopy post-acute diverticulitis is advised.
  • Celiac disease surveillance protocols are updated.
  • Tofacitinib is effective for ulcerative colitis, with precautions.
  • Budesonide tablets are validated for eosinophilic esophagitis.

Conclusions:

  • The year 2019 brought several critical updates impacting the management of diverse gastrointestinal and hepatological conditions.
  • Clinicians should be aware of these advancements for optimal patient care.

Related Concept Videos

Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.8K
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
616
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
1.1K
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
256
Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
999
Hepatic Portal System01:21

Hepatic Portal System

The hepatic portal system, a critical part of our circulatory framework, transports nutrient-laden, deoxygenated blood from the gastrointestinal tract and spleen to the liver. This ingenious system plays an indispensable role in maintaining our body's metabolic equilibrium.
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...
4.9K