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Related Concept Videos

Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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Chronic Kidney Disease III: Interprofessional Care01:28

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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Acute Kidney Injury V: Interprofessional Care01:20

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Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Chronic Kidney Disease I: Introduction01:25

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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Renal Drug Clearance: Overview01:06

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Renal clearance is a crucial parameter in pharmacokinetics that quantifies the rate at which the kidneys excrete a drug. It represents a constant fraction of the central volume of distribution containing the drug that the kidney eliminates per unit of time.
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Chronic Kidney Disease IV: Nursing Management01:18

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Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
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Related Experiment Video

Updated: Dec 30, 2025

Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches
06:51

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[Nephrology : what's new in 2019 ?]

Patrick Saudan1, Sophie De Seigneux1, Karine Hadaya1

  • 1Service de néphrologie, Département de médecine, HUG, 1211 Genève 14.

Revue Medicale Suisse
|January 22, 2020
PubMed
Summary

New kidney disease treatments show promise. Gliflozines aid diabetic nephropathy, rituximab treats membranous nephropathy, and roxadustat may help renal anemia. Kidney transplants and immunosuppression strategies are also discussed.

Area of Science:

  • Nephrology
  • Transplantation immunology
  • Pharmacology

Background:

  • Diabetic nephropathy and membranous nephropathy are significant kidney diseases.
  • Renal anemia is a common complication in kidney disease patients.
  • Kidney transplantation remains a vital treatment option for end-stage renal disease.

Purpose of the Study:

  • To review recent advancements in nephrology treatments.
  • To evaluate the efficacy and safety of novel therapeutic agents.
  • To explore updated strategies in kidney transplantation and immunosuppression.

Main Methods:

  • Review of current clinical studies and pharmacological data.
  • Analysis of treatment outcomes for various nephropathies.
  • Assessment of immunosuppressive protocols in renal transplantation.

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Main Results:

  • Gliflozines demonstrate efficacy in treating diabetic nephropathy.
  • Rituximab is effective for membranous nephropathy.
  • Roxadustat shows potential for treating renal anemia.
  • Long-acting erythropoietins may increase mortality in hemodialysis patients.
  • HCV-seropositive donor kidneys can be utilized for transplantation.
  • Everolimus-based immunosuppression can minimize calcineurin inhibitor use.

Conclusions:

  • Several novel therapeutic agents offer new hope for kidney disease patients.
  • Optimized immunosuppression and organ utilization are key in transplantation.
  • Careful consideration of erythropoietin formulations is necessary for hemodialysis patients.