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Self-assembly of porphyrins on nucleic acid templates
E J Gibbs1, I Tinoco, M F Maestre
1Department of Chemistry, Goucher College, Towson, MD 21204.
Biochemical and Biophysical Research Communications
|November 30, 1988
Abstract:
The cis and trans isomers of dicationic bis(4-N-methylpyridyl)diphenylporphine show a much greater tendency to aggregate than similar tetracationic porphyrins. Upon binding to nucleic acids these aggregating dicationic porphyrins form long-range structures on the polymer template giving intense circular dichroism signals whose profile reports the helical sense of the DNA.