INTERNAL DOSIMETRY TOOL FOR THE IMPLEMENTATION AND USE OF NEW ICRP/OIR MODELS: A CAESIUM STUDY

Area of Science:

• Medical Physics
• Radiation Protection
• Computational Biology

Background:

• Accurate dose assessment following radioactive material intake relies on understanding radionuclide distribution.
• International Commission on Radiological Protection (ICRP) models are crucial for internal dosimetry, with recent updates in the 'Occupational Intakes of Radionuclides (OIR)' series.

Purpose of the Study:

• To implement the updated ICRP caesium model into a user-friendly computer package.
• To develop features for estimating radionuclide intake and dose from bioassay data.
• To provide statistical indicators for assessing the goodness-of-fit in dose assessment.

Main Methods:

• Implementation of the ICRP caesium model within the BIOKMOD toolbox, creating the ICRP130Models package.
• Development of algorithms to estimate best-fitted intake and committed effective dose.
• Inclusion of chi-squared test and p-value calculations for fit assessment.

Main Results:

• Successful integration of the new caesium model into the ICRP130Models software.
• The software provides estimations of intake and committed effective dose.
• The package offers goodness-of-fit indicators (chi-squared, p-value) for robust assessment.

Conclusions:

• The ICRP130Models software facilitates accurate internal dose assessment using updated ICRP models.
• The tool enhances the estimation of occupational intake and dose from bioassay measurements.
• Parametric model customization allows for flexible fitting of bioassay data.