Enteral nutrition in cystic fibrosis
Angelika Kędzior1, Beata Łabuz-Roszak2, Sylwia Jezierska3
1Katedra i Zakład Podstawowych Nauk Medycznych, Wydział Zdrowia Publicznego w Bytomiu, Śląski Uniwersytet Medyczny w Katowicach, Bytom, Polska
Insights
Enteral nutrition significantly benefits cystic fibrosis patients who struggle with weight gain on high-energy diets. This method improves quality of life and reduces respiratory infections with minimal side effects.
Area of Science:
- Medical Science
- Nutrition Science
- Genetics
Background:
- Cystic fibrosis (CF) is a genetic disorder requiring comprehensive management.
- Early detection through newborn screening enables prompt treatment.
- Nutritional support is a critical component of CF therapy.
Purpose of the Study:
- To evaluate the benefits and risks of enteral nutrition in cystic fibrosis patients.
- To assess the impact of enteral nutrition on weight, quality of life, and infection rates in CF patients.
Main Methods:
- A study involving 53 cystic fibrosis patients (15 males, 38 females).
- Inclusion criteria: at least one month of enteral nutrition, underweight, and no weight gain on high-energy oral diet.
- Data collected using a self-constructed questionnaire.
Main Results:
- Median weight gain of 7 kg was observed with enteral nutrition.
- Over 79% reported no side effects; minor issues included local infections and balloon prolapse.
- All patients reported benefits, primarily weight gain and improved quality of life.
- 41.5% experienced a decrease in respiratory infection frequency.
Conclusions:
- Enteral nutrition is an effective strategy for cystic fibrosis patients unresponsive to high-energy oral diets.
- It leads to significant weight gain, enhanced quality of life, and potentially fewer respiratory infections.
- The method is well-tolerated with a low incidence of adverse events.
Introduction:
Cystic fibrosis is a genetically determined disease. It is currently detected right after birth thanks to a screening program. This early detection allows for quick treatment inclusion. Cystic fibrosis therapy has a comprehensive character. The way of nutrition is also very important. The aim of this study was to evaluate the benefits and risks of enteral nutrition in patients with cystic fibrosis.
Material And Methods:
53 people with cystic fibrosis participated in the study (15 men, 38 women). Qualification for the study required the fulfillment of three conditions: enteral nutrition used for at least one month, no increase in body weight when using a high energy diet, underweight. The research was carried with use of self-constructed questionnaire.
Results:
The mean age of the respondents was 19.9 ± 4 years. The median weight gain after enteral nutrition was 7 kg. Most (n = 42, 79.2%) did not report any side effects. Few reported local infections (n = 9; 17%) or prolapse of the balloon (n = 2, 3.8%). On the other hand, everyone reported benefits - it was mainly weight gain and improved quality of life. In some cases (n = 22, 41.5%) with the use of enteral nutrition, a decrease in the frequency of respiratory infections was observed.
Conclusions:
Enteral nutrition is a beneficial method in those patients with cystic fibrosis, in whom high-energy oral nutrition is inefficient.
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