Related Experiment Video
Updated: Dec 29, 2025

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
Published on: June 17, 2015
It's Just Math-Unless It's Toxic!
Kayla Myers1, Elisabeth Giblin2, Michele Zell-Kanter3
1Rosalind Franklin University and Northwestern Memorial Hospital Chicago IL.
Emergency medicine residents struggle with pharmaceutical calculations, potentially impacting patient safety. Reliance on resources like Google and pharmacy staff is common, increasing with training level.
Area of Science:
- Medical Education
- Emergency Medicine
- Pharmacology
Background:
- Accurate pharmaceutical calculations are critical for safe medication administration in emergency medicine.
- Assessing the competency of emergency medicine residents in performing these calculations is essential for patient safety.
Purpose of the Study:
- To evaluate the proficiency of emergency medicine residents in executing pharmaceutical calculations.
- To identify the resources emergency medicine residents utilize for pharmaceutical calculations.
Main Methods:
- A needs-assessment survey with six pharmaceutical calculation questions was administered to emergency medicine residents at a 2016 citywide conference.
- Participants' accuracy in calculations and their preferred resources (e.g., internet, clinical pharmacy staff) were recorded.
Main Results:
- Nearly 80% of residents answered at least four out of six calculations correctly, with higher accuracy in postgraduate years 2-4.
- A significant percentage of residents, particularly in earlier training years, considered accurate calculations very important.
- Internet resources and clinical pharmacy (PharmD) staff were frequently used for dose calculations, with usage increasing with training level.
Conclusions:
- Emergency medicine residents demonstrated suboptimal performance in pharmaceutical calculations, posing a risk for patient morbidity and mortality.
- Increased reliance on external resources like the internet and pharmacy staff for calculations was observed with higher postgraduate years.
- Clinical pharmacy services are extensively utilized by residents across all training levels.
More Related Videos
Related Concept Videos
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
The Periodic Table and Organismal Elements
Periodic Table Provides Information...
The Periodic Table and Organismal Elements
Fundamental Mathematical Principles in Pharmacokinetics: Mathematical Expressions and Units
One significant application of mathematics in pharmacokinetics is the characterization of drug distribution through the volume of distribution...
Fundamental Mathematical Principles in Pharmacokinetics: Calculus and Graphs
On the other hand, integral calculus focuses on...

