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Ocular Manifestations in Late Onset Behçet's Disease
Dorsaf Saadouli1, Khaoula Ben Mansour1, Salem Yahyaoui1
1Department of Ophthalmology, Faculty of Medicine of Tunis, La Rabta Hospital, University of Tunis, El Manar, Tunisia.
Current Aging Science
|January 30, 2020
Summary
Late-onset Behçet disease in Tunisia presents with significant ocular issues, including uveitis and macular involvement. Despite perceptions of mildness, 10.5% of patients experienced blindness, highlighting the need for vigilance.
Area of Science:
- Ophthalmology
- Rheumatology
- Immunology
Background:
- Behçet's disease is prevalent in Tunisia and can severely impact vision and life.
- Late-onset Behçet's disease is uncommon and understudied.
- Understanding its demographic and ocular features is crucial for prognosis.
Purpose of the Study:
- To analyze the demographic characteristics of late-onset Behçet disease patients in Tunisia.
- To investigate the specific ocular manifestations in this patient group.
- To evaluate treatment outcomes and complications.
Main Methods:
- Retrospective study of 21 oculo-Behçet patients over seven years.
- Analysis of demographic data, onset symptoms, and ocular involvement.
- Review of treatment strategies and visual outcomes.
Main Results:
- Mean age was 54.81 years, with a M/F ratio of 2.5.
- Ocular manifestations were dominated by uveal involvement (30 eyes), particularly panuveitis (13 eyes).
- Macular involvement affected 8 patients (14 eyes), and 10.5% experienced blindness.
Conclusions:
- Late-onset Behçet disease in Tunisia can lead to severe visual impairment, contrary to expectations of a milder course.
- Posterior uveitis and panuveitis are the most common ocular lesions.
- Aggressive management with corticosteroids and immunosuppressants is essential.
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