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CADASIL presenting as late-onset mania with anosognosia
Manik Uppal1, Dora Kanellopoulos1, Nabil Kotbi1
1Weill Cornell Medical College New York Presbyterian Hospital New York NY USA.
Abstract:
The diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) should be considered in patients with late-onset personality change and mania. However, neuropsychological deficits precipitated by the disorder pose significant challenges to recognition and appropriate management of CADASIL in susceptible patients.
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