Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetic Screens02:46

Genetic Screens

5.5K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.5K
Human Genetics01:28

Human Genetics

1.3K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.3K
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

918
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
918
What is Genetic Engineering?00:49

What is Genetic Engineering?

79.4K
Overview
79.4K
Genomics02:02

Genomics

39.5K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.5K
Genetic Lingo01:11

Genetic Lingo

113.3K
Overview
113.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A complex case of chronic cutaneous <i>Borrelia burgdorferi</i> sensu stricto infection manifesting as morphea-like sclerosis in the United States.

JAAD case reports·2026
Same author

A novel out-of-frame CREBBP::TRAP1 fusion in malignant intracerebral nerve sheath tumor.

Journal of neuropathology and experimental neurology·2026
Same author

Development of a multiplex ddPCR assay for simultaneous absolute quantification of bacterial, fungal, and human DNA.

PloS one·2026
Same author

Sclerosing melanocytic tumors with MAP2K1 in frame deletions and 15q gains: A distinctive pathway of nevogenesis with reproducible morphology.

Virchows Archiv : an international journal of pathology·2025
Same author

A Systematic, Evidence-Based Workflow for Classifying KMT2A Fusions in Acute Myeloid Leukemia.

The Journal of molecular diagnostics : JMD·2025
Same author

Novel Homozygous Full Gene Deletion of SLC12A5 in a Newborn With Refractory Seizures.

American journal of medical genetics. Part A·2025
Same journal

Advances in Hemostasis Laboratory Testing.

Clinics in laboratory medicine·2026
Same journal

Extracellular Vesicles in Hemostasis.

Clinics in laboratory medicine·2026
Same journal

Thrombin Generation Assay: Ready for Prime Time.

Clinics in laboratory medicine·2026
Same journal

Viscoelastic Testing for the Laboratorian: Recent Advances and Practical Advice.

Clinics in laboratory medicine·2026
Same journal

Practical Recommendations for Harmonization of Hemostasis Testing Across Hospital Sites.

Clinics in laboratory medicine·2026
Same journal

The Role of Hypoxia in Vascular Endothelial Dysfunction and Venous Thromboembolism.

Clinics in laboratory medicine·2026
See all related articles

Related Experiment Video

Updated: Dec 29, 2025

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.4K

Lessons Learned from Direct-to-Consumer Genetic Testing.

Lauren M Petersen1, Joel A Lefferts1

  • 1Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, NH 03756, USA.

Clinics in Laboratory Medicine
|February 4, 2020
PubMed
Summary
This summary is machine-generated.

Direct-to-consumer genetic testing is rising, but concerns exist about its accuracy and clinical relevance. Further research is needed to assess long-term impacts and inform potential regulations for these genetic tests.

Keywords:
BRCA1BRCA2CancerDirect-to-consumer genetic testing

More Related Videos

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

34.5K
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.5K

Related Experiment Videos

Last Updated: Dec 29, 2025

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.4K
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

34.5K
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.5K

Area of Science:

  • Genetics
  • Consumer Health
  • Regulatory Science

Background:

  • Increasing availability of direct-to-consumer (DTC) genetic testing.
  • Growing concerns regarding the clinical validity and utility of DTC genetic tests.
  • Debate on whether DTC companies should offer tests previously exclusive to medical settings.

Purpose of the Study:

  • To evaluate the potential risks and limitations associated with DTC genetic testing.
  • To examine the understanding of results by consumers using DTC genetic services.
  • To determine the necessity for enhanced regulatory oversight of DTC genetic testing.

Main Methods:

  • Review of current literature on DTC genetic testing accuracy and consumer comprehension.
  • Analysis of the clinical relevance and potential inaccuracies of DTC genetic test results.
  • Assessment of the existing regulatory landscape for genetic testing services.

Main Results:

  • DTC genetic tests can be incomplete, inaccurate, and inappropriate for consumer use.
  • The clinical utility of DTC genetic testing is currently very limited.
  • Consumer understanding of DTC genetic test results is often unclear.

Conclusions:

  • Further research is essential to understand the long-term effects of DTC genetic testing.
  • Stricter regulations may be required to ensure the safety and efficacy of DTC genetic tests.
  • The current limitations highlight the need for caution in the provision and interpretation of DTC genetic information.