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Thrombolytic therapy in acute arterial thrombosis
C Price1, M A Jacocks, T Tytle
1Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City.
American Journal of Surgery
|December 1, 1988
Summary
Thrombolysis for acute arterial thrombosis is effective, with 17 of 20 attempts succeeding angiographically. Successful treatment and correction of arterial lesions led to better patient outcomes and fewer amputations, emphasizing careful monitoring to reduce complications.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiovascular Medicine
Background:
- Acute arterial thrombosis poses a significant risk of limb loss.
- Thrombolysis offers a less invasive approach to restoring arterial blood flow.
Purpose of the Study:
- To evaluate the safety and efficacy of thrombolysis for acute arterial thrombosis.
- To identify factors influencing patient outcomes after thrombolysis.
Main Methods:
- Retrospective review of 17 patients undergoing 20 thrombolysis attempts for acute arterial thrombosis.
- Angiographic assessment of thrombolysis success.
- Analysis of patient outcomes in relation to lesion correctability and procedural success.
Main Results:
- Seventeen of 20 thrombolysis attempts were angiographically successful.
- Patients with correctable lesions and reconstructive procedures showed improved outcomes.
- Successful thrombolysis correlated with reduced need for amputation.
Conclusions:
- Thrombolysis is a safe and effective treatment for acute arterial thrombosis.
- Careful patient monitoring is crucial for minimizing complications.
- Optimal outcomes are achieved when thrombolysis is combined with correction of underlying arterial lesions.