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Updated: Dec 29, 2025

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
Published on: June 13, 2025
Long-Term Outcomes of Arm Replantation.
Chunyang Wang, Morad Askari1, Feng Zhang2
1Joseph M. Still Burn and Reconstruction Center, Miami, FL.
Arm replantation survival is improving, but functional outcomes vary. This review found that nearly half of patients achieve satisfactory results, often requiring multiple secondary surgeries and extensive recovery periods.
Area of Science:
- Microsurgery
- Orthopedic Surgery
- Reconstructive Surgery
Background:
- Microsurgery advances have increased arm replantation survival rates.
- Functional outcomes following arm replantation remain unpredictable.
- Secondary reconstructive procedures are often necessary after initial replantation.
Purpose of the Study:
- To systematically review the long-term functional outcomes of arm replantation.
- To evaluate the types, timing, and impact of secondary reconstructive procedures.
- To identify factors influencing the overall success of arm replantation.
Main Methods:
- Systematic review of English literature from PubMed, Embase, and CENTRAL databases.
- Inclusion of studies with successful arm replantation and >1 year follow-up.
- Extraction and analysis of clinical data, including functional outcomes and secondary surgeries.
Main Results:
- 79 arm replantations across 29 studies were analyzed.
- A total of 111 secondary procedures were performed, averaging 2.6 per patient.
- Nerve repair, muscle transfer, and tendon transfer were common secondary procedures; distal amputations and sharp-cut injuries yielded better outcomes.
Conclusions:
- Optimal functional outcomes are achievable in approximately 49.4% of arm replantation patients.
- Multiple secondary surgical interventions and prolonged recovery are frequently required.
- Amputation level and injury type significantly impact final functional results.
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