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Updated: Dec 29, 2025

A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium
Published on: May 18, 2021
Burden of Disease due to Nonalcoholic Fatty Liver Disease
Mark D Muthiah1, Arun J Sanyal2
1Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Drive, Singapore 117597; Division of Gastroenterology and Hepatology, National University Hospital, National University Health System, 1E Kent Ridge Road, Level 10 Tower Block, 119228, Singapore.
Abstract:
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most common liver disease in both Western populations and other parts of the world. This review discusses the prevalence and incidence of NAFLD in various regions around the world. The methodology used to identify the epidemiology and classify the stages of the disease is described. The impact of the disease on individuals, looking at both liver-related and extrahepatic consequences of the disease, is then discussed. Finally, the economic and societal impact of the disease is discussed.
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