Chronic Diabetes Complications: The Need to Move beyond Classical Concepts
Dídac Mauricio1, Núria Alonso2, Mònica Gratacòs3
1DAP-Cat group, Unitat de Suport a la Recerca Barcelona, Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Barcelona, Spain; Department of Endocrinology and Nutrition, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain.
Trends in Endocrinology and Metabolism: TEM
|February 9, 2020
Summary
Diabetic complications affect blood vessels and also cause overlooked issues like nerve damage, organ dysfunction, and cognitive decline. A holistic approach is crucial for comprehensive diabetes patient care.
Area of Science:
- Endocrinology
- Nephrology
- Cardiology
- Neurology
Background:
- Diabetic complications impact both microvascular and macrovascular systems.
- Target organs show large vessel injury and microangiopathic changes.
- Non-vascular complications of diabetes are frequently underestimated.
Purpose of the Study:
- To highlight overlooked diabetic complications beyond vascular damage.
- To advocate for a holistic view of diabetes management.
- To emphasize the importance of considering all organ systems in diabetes care.
Main Methods:
- Review of existing literature on diabetes complications.
- Analysis of non-classical clinical repercussions.
- Synthesis of current understanding of diabetes pathophysiology.
Main Results:
- Identified neuronal, interstitial, and metabolic damage as key non-vascular complications.
- Highlighted conditions like cognitive decline, pulmonary dysfunction, and cancer risk.
- Emphasized the simultaneous micro- and macrovascular compromise.
Conclusions:
- Diabetes management requires a holistic perspective, addressing vascular and non-vascular complications.
- Healthcare providers must consider all potential organ involvements and clinical repercussions.
- Integrated patient care is essential for managing the multifaceted nature of diabetes.
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