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Updated: Dec 28, 2025
Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Recent advances in metal-catalysed asymmetric sequential double hydrofunctionalization of alkynes
Zhaoyang Cheng1, Jun Guo1, Zhan Lu1
1Department of Chemistry, Zhejiang University, Hangzhou 310027, China. luzhan@zju.edu.cn.
Abstract:
In recent years, metal-catalysed asymmetric sequential double hydrofunctionalization of alkynes (ASDHA) has emerged as a powerful strategy to construct valuable chiral products in an atom- and pot-economic manner utilizing readily available feedstocks. In this feature article, recent progress made in this field will be overviewed. Attention will be given to the background, substrate scopes, applications, advances and mechanistic investigations of various asymmetric sequential double hydrofunctionalizations of alkynes.
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