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Updated: Dec 27, 2025

Translational Orthotopic Models of Glioblastoma Multiforme
Published on: February 17, 2023
Glomangioma of Uncertain Malignant Potential: A Case Report
Meghan McCullough1, Bonnie Balzer2, Stuart H Kuschner3
1Division of Plastic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Abstract:
Glomus tumors are rare benign tumors which commonly affect the hand but are seldom seen extradigitally. Less commonly seen is the glomangioma, a variant of benign glomus tumor, and even rarer is the glomangiosarcoma, a malignant variant. Determining malignancy can be difficult and an intermediate diagnosis, glomus tumor of uncertain malignant potential, has been proposed. We present a case of a 56-year-old male with a recurrent forearm mass diagnosed as a glomangioma of uncertain malignant potential. Although the characteristics and behavior of malignant cases are still incompletely understood, it is important that a high index of suspicion be maintained when approaching these tumors, especially when large or recurrent. Glomangiomas should be included in the differential diagnosis when evaluating soft tissue masses in the forearm and should be evaluated for malignant features.

