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[Successful Systemic Lysis Therapy in Acute Retinal Arterial Occlusions]
Florian Philipp Raber1, Katharina Reinking2, Steffen Schmitz-Valckenberg2
1Klinik für Augenheilkunde, Universitätsklinikum Ulm.
Klinische Monatsblatter Fur Augenheilkunde
|February 25, 2020
Summary
Systemic intravenous fibrinolysis can restore vision in acute retinal artery occlusion cases. Early treatment within hours of symptom onset shows significant visual acuity improvement and potential vision preservation.
Area of Science:
- Ophthalmology
- Vascular Medicine
- Emergency Medicine
Background:
- Retinal artery occlusion causes irreversible vision loss with no standard therapy.
- German guidelines permit intravenous fibrinolysis within 4.5 hours for retinal artery occlusions.
Purpose of the Study:
- To evaluate the efficacy of systemic intravenous fibrinolysis in acute retinal artery occlusion.
- To report outcomes in two patients treated with this approach.
Main Methods:
- Two patients with acute retinal artery occlusion received systemic intravenous fibrinolysis.
- Treatment timing varied based on symptom onset and clinical presentation.
Main Results:
- Patient 1 (branch retinal artery occlusion) showed immediate symptom improvement and good retinal function post-treatment.
- Patient 2 (central retinal artery occlusion) experienced initial deterioration but improved visual acuity and visual field preservation after emergency lysis therapy.
- Both patients demonstrated marked visual acuity improvement directly following fibrinolysis.
Conclusions:
- Systemic intravenous fibrinolysis is a successful treatment for acute retinal artery occlusion.
- Prompt administration of fibrinolysis can lead to significant visual recovery and preservation.
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