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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Imaging Studies III: Computed Tomography01:27

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Updated: Dec 27, 2025

Microfocus X-ray CT microCT Imaging of Actinia equina Cnidaria, Harmothoe sp. Annelida, and Xenoturbella japonica Xenacoelomorpha
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X-ray computed tomography in life sciences.

Shelley D Rawson1, Jekaterina Maksimcuka1, Philip J Withers1

  • 1The Henry Royce Institute and School of Materials, The University of Manchester, Manchester, M13 9PL, UK.

BMC Biology
|February 28, 2020
PubMed
Summary
This summary is machine-generated.

Micro-computed tomography (μCT) now images tissues in 3D and 4D at high resolutions. Enhanced contrast methods enable detailed soft tissue visualization for life sciences research.

Keywords:
3D histology3D imagingCorrelative microscopyElemental mappingLightsheetPhase contrastQuantitative tomographyTime-lapse tomographyWater windowX-ray computed tomography

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Area of Science:

  • Life Sciences Imaging
  • Biomedical Imaging
  • Microscopy

Background:

  • Micro-computed tomography (μCT) is advancing imaging capabilities.
  • High-resolution 3D and 4D imaging of tissues is increasingly important.
  • Improving soft tissue contrast in μCT is a key challenge.

Purpose of the Study:

  • To review recent advancements in micro-computed tomography (μCT) for life sciences.
  • To highlight new capabilities in soft tissue contrast enhancement.
  • To discuss future directions and benefits for the life sciences community.

Main Methods:

  • Review of recent developments in micro-computed tomography (μCT) techniques.
  • Focus on methods for enhancing soft tissue contrast.
  • Analysis of applications in virtual histology, live cell, subcellular, and correlative imaging.

Main Results:

  • μCT now achieves micron and sub-micron resolutions in 3D and 4D.
  • New methods significantly improve soft tissue contrast.
  • Enabled applications include virtual histology and live cell imaging.

Conclusions:

  • Recent μCT developments offer unprecedented imaging capabilities for life sciences.
  • Enhanced soft tissue contrast is crucial for detailed biological studies.
  • Future advancements promise further benefits for researchers.