Related Experiment Video
Updated: Dec 27, 2025
07:54
Isolation of Neonatal Extrahepatic Cholangiocytes
Published on: June 5, 2014
10.7K
A Twisted Case Of Jaundice.
1Internal Medicine, Methodist Health System, Dallas, USA.
Cureus
|February 28, 2020
Summary
Obstructive jaundice in the elderly can rarely be caused by diaphragmatic hernias (DH). This case highlights a rare presentation of DH causing biliary obstruction, managed non-surgically with improved jaundice.
Area of Science:
- Gastroenterology and Hepatology
- Surgical Case Reports
Background:
- Diaphragmatic hernias (DH) are uncommon causes of abdominal emergencies.
- Obstructive jaundice in the elderly is typically associated with other pathologies, making DH a rare differential diagnosis.
Observation:
- A 71-year-old female presented with painless jaundice, early satiety, and weight loss.
- Imaging revealed common bile duct dilation due to external compression from a diaphragmatic hernia.
Findings:
- The diaphragmatic hernia caused mechanical biliary obstruction.
- Non-surgical management with biliary decompression and stenting significantly improved jaundice.
Implications:
- Clinicians should consider rare anatomic anomalies like diaphragmatic hernias in elderly patients presenting with obstructive jaundice.
- Non-surgical management can be a viable option for patients with prohibitive surgical risks.
Related Concept Videos
01:26Diseases of the Liver and Gallbladder
1.8K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.8K
01:14Changes in Skin Color: Clinical Perspectives
3.2K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.2K
01:17Gallbladder
1.8K
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
1.8K
01:27Disorders of Erythrocytes
2.0K
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
2.0K
01:20Inborn Errors of Metabolism
636
Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
636
01:19Rh Blood Group
2.6K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
2.6K