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Updated: Dec 27, 2025

Author Spotlight: Efficiently Eliminating Bacteriophages from Infected Salmonella Cultures Using Lipopolysaccharides
Published on: June 28, 2024
[Antibacterial applications of bacteriophages]
Mireille Ansaldi1, Pascale Boulanger2, Charlotte Brives3
1Centre national de la recherche scientifique, Aix-Marseille Université, Institut de microbiologie de la Méditerranée, UMR7283, Laboratoire de chimie bactérienne, 31 chemin Joseph Aiguier, 13402 Marseille Cedex 9, France.
Abstract:
In the 1917 article in which Félix d'Hérelle describes his first observations and proposes the name of bacteriophage, he also reports the first use of these viruses to treat bacterial infections, thus giving birth to phage therapy. Soon after antibiotics supplanted bacteriophages. Today, bacteria resistant to multiple antibiotics become a growing public health issue worldwide. This situation has revived research aiming at developing the antibacterial activity of bacteriophages to treat patients as well as diseases in animals and plants. In fact, the areas of applications of bacteriophages as antibacterial are widening as current solutions of chemical nature are questioned. This review summarizes the basic principles of therapeutic applications of bacteriophages and presents recent data in areas where commercial exploitation is occurring or about to emerge.
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