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Related Experiment Video

Updated: Dec 27, 2025

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Intraoperative Floppy Iris Syndrome: Updated Perspectives.

Chrysanthos D Christou1, Ioannis Tsinopoulos1, Nikolaos Ziakas1

  • 12nd Department of Ophthalmology, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, Greece.

Clinical Ophthalmology (Auckland, N.Z.)
|February 29, 2020
PubMed
Summary

Intraoperative floppy iris syndrome (IFIS) is a surgical challenge linked to various medications and patient factors. Preoperative risk assessment and management are crucial for preventing visual complications during cataract surgery.

Keywords:
IFISintraoperative floppy iris syndromeintraoperative managementpreoperative prophylaxisrisk factors

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Area of Science:

  • Ophthalmology
  • Surgical Science

Background:

  • Intraoperative floppy iris syndrome (IFIS) remains a significant challenge in phacoemulsification surgery.
  • Initially linked to tamsulosin, IFIS is now associated with numerous risk factors, complicating surgical management.

Purpose of the Study:

  • To highlight the persistent challenges of IFIS in cataract surgery.
  • To emphasize the importance of preoperative risk stratification and management strategies.

Main Methods:

  • Review of known risk factors for IFIS, including medications and patient demographics.
  • Discussion of multidisciplinary approaches and joint statements from professional ophthalmological societies.

Main Results:

  • IFIS is correlated with gender, age, hypertension, alpha-1 adrenergic receptor antagonists, finasteride, angiotensin II receptor inhibitors, benzodiazepines, antipsychotics, and reduced pupil dilation.
  • A comprehensive understanding of these risk factors is essential for surgical planning.

Conclusions:

  • Preoperative risk assessment, documentation, and tailored management are critical for mitigating IFIS.
  • Multidisciplinary collaboration and awareness of IFIS risk factors can prevent significant visual morbidity.