Related Experiment Video
Updated: Dec 27, 2025

Light-Induced In Situ Transmission Electron Microscopy for Observation of the Liquid-Soft Matter Interaction
Published on: July 26, 2022
A Technical Introduction to Transmission Electron Microscopy for Soft-Matter: Imaging, Possibilities, Choices, and
Linda E Franken1, Kay Grünewald1, Egbert J Boekema2
1Department of Structural Cell Biology of Viruses, Heinrich-Pette Institute-Leibniz-Institute of Experimental Virology University of Hamburg, Centre for Structural Systems Biology, Notkestraße 85, 22607, Hamburg, Germany.
Transmission electron microscopy (TEM) is a vital structural analysis tool across many sciences. Recent technical advances enhance its capabilities, especially for soft matter chemistry applications.
Area of Science:
- Material Sciences
- Physics
- Soft Matter Chemistry
- Biology
Background:
- Transmission electron microscopy (TEM) is a fundamental structural analysis tool with broad applications.
- Its ability to visualize structures from micrometers to angstroms makes it indispensable.
- Continuous technical advancements are expanding its research potential.
Purpose of the Study:
- To summarize technical considerations for electron imaging.
- To highlight recent advances in electron microscopy.
- To explore applications in soft matter chemistry.
Main Methods:
- Review of electron optics and technology.
- Discussion of sample preparation and processing.
- Analysis of recent technological developments.
Main Results:
- TEM remains a cornerstone methodology in science.
- Technical improvements enhance imaging capabilities.
- New applications are emerging, particularly in soft matter.
Conclusions:
- Electron microscopy is crucial for structural analysis.
- Ongoing innovations are broadening its scientific impact.
- Soft matter chemistry benefits significantly from advanced TEM techniques.
More Related Videos
08:04Preparation and Observation of Thick Biological Samples by Scanning Transmission Electron Tomography
Published on: March 12, 2017
10:23Author Spotlight: A Machine-Vision Approach to Transmission Electron Microscopy Workflows, Results Analysis and Data Management
Published on: June 23, 2023
Related Concept Videos
Transmission Electron Microscopy
Electron Microscope Tomography and Single-particle Reconstruction
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Overview of Electron Microscopy
Overview of Microscopy Techniques
Preparation of Samples for Electron Microscopy
Cryo-electron Microscopy