Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.5K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.5K
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

4.9K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
4.9K
Tissue Transplantation01:24

Tissue Transplantation

813
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
813
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.1K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Next-generation osteosarcoma models for precision medicine.

Communications biology·2026
Same author

Stem cell-derived secretome: a novel strategy for wound healing.

Frontiers in pharmacology·2026
Same author

Hydrogel-Forming Ability and Biological Characterization of Exopolysaccharide (EPS) from <i>Porphyridium cruentum</i>.

Gels (Basel, Switzerland)·2026
Same author

Electrospun nanofibers and electrical stimulation: a synergistic approach for chronic wound management.

Journal of materials chemistry. B·2026
Same author

Bioactive and Injectable Granular Hydrogels Incorporating Decellularized Extracellular Matrix.

ACS biomaterials science & engineering·2026
Same author

Impact of storage techniques on ovine temporomandibular joint discs composition and physicochemical properties.

Frontiers in bioengineering and biotechnology·2025

Related Experiment Video

Updated: Dec 27, 2025

Experimental Approaches to Tissue Engineering
16:41

Experimental Approaches to Tissue Engineering

Published on: August 30, 2007

6.7K

In situ Enabling Approaches for Tissue Regeneration: Current Challenges and New Developments.

Juliana R Dias1, Nilza Ribeiro2, Sara Baptista-Silva2

  • 1Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria, Leiria, Portugal.

Frontiers in Bioengineering and Biotechnology
|March 6, 2020
PubMed
Summary

In situ tissue regeneration uses biomaterials at defect sites. Advanced strategies like 3D/4D bioprinting offer improved tissue mimicry over conventional methods.

Keywords:
bioprintingcomputer/non-computer assisted approachesin situ approachesin situ biomaterialstissue regeneration

More Related Videos

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
09:43

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

10.4K
Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber
09:55

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber

Published on: May 30, 2016

9.2K

Related Experiment Videos

Last Updated: Dec 27, 2025

Experimental Approaches to Tissue Engineering
16:41

Experimental Approaches to Tissue Engineering

Published on: August 30, 2007

6.7K
Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
09:43

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

10.4K
Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber
09:55

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber

Published on: May 30, 2016

9.2K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • In situ tissue regeneration involves implanting biomaterials at defects, utilizing the body's microenvironment.
  • Traditional methods relied on particles or gels, with limitations in mimicking native tissue structures.
  • Recent focus on bioinks and bioprinting for in situ regeneration, yet often lacks integration of diverse technologies.

Purpose of the Study:

  • To provide a comprehensive review of current and advanced in situ tissue regeneration strategies.
  • To discuss limitations of conventional approaches and highlight potential of advanced methods.
  • To explore future trends and research challenges in in situ regeneration.

Main Methods:

  • Review of literature on in situ tissue regeneration strategies.
  • Analysis of conventional and advanced techniques, including bioinks, bioprinting, and hybrid approaches.
  • Discussion of in vitro and in vivo evidence for different strategies.

Main Results:

  • Conventional methods (e.g., stem cell recruitment) show limitations in mimicking native tissue.
  • Advanced strategies like 3D/4D bioprinting and hybrid approaches show promise in overcoming these limitations.
  • The integration of multiple technologies is crucial for true in situ regeneration.

Conclusions:

  • In situ tissue regeneration holds significant potential for repairing damaged tissues.
  • Advanced bioprinting and hybrid strategies are key to achieving better functional tissue restoration.
  • Further research is needed to address challenges and optimize in situ regeneration approaches for clinical translation.