Related Experiment Video
Updated: Dec 27, 2025
Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
Published on: November 25, 2015
Catalytic formation of luminescent lanthanide complexes using an entropy-driven DNA circuit
Yusuke Kitamura1, Yukina Azuma, Yousuke Katsuda
1Division of Materials Science and Chemistry, Faculty of Advanced Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan. ykita@kumamoto-u.ac.jp toshi@chem.kumamoto-u.ac.jp.
Abstract:
Two DNA conjugates modified with ethylenediaminetetraacetic acid and 1,10-phenanthroline were prepared as a pair of split probes. They were designed to form a duplex with their auxiliary groups facing each other, providing a microenvironment to accommodate lanthanide ions. The luminescent signal was amplified by catalytic duplex formation based on an entropy-driven DNA circuit.
