Related Experiment Video
Updated: Dec 27, 2025
08:39
Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
26.2K
Severe Lung Injury Associated With Use of e-Cigarette, or Vaping, Products-California, 2019
Amy Heinzerling1,2, Christina Armatas1, Ellora Karmarkar2,3
1Center for Healthy Communities, California Department of Public Health, Richmond.
JAMA Internal Medicine
|March 7, 2020
Summary
E-cigarette, or vaping, product use-associated lung injury (EVALI) affected 160 Californians, with most using THC products from informal sources. Vitamin E acetate was common in THC products, but other causes of EVALI remain possible.
Area of Science:
- Public Health
- Pulmonology
- Toxicology
Background:
- E-cigarette, or vaping, product use-associated lung injury (EVALI) has led to over 2700 hospitalizations in the U.S. since August 2019.
- California has a high number of EVALI cases and a legal adult-use cannabis market, making it a key area for investigation.
Purpose of the Study:
- To characterize the clinical presentation of EVALI patients in California.
- To identify specific vaping product exposures linked to EVALI in this population.
Main Methods:
- A case series was conducted, analyzing data from 160 hospitalized EVALI patients reported in California between August and November 2019.
- Standardized interviews assessed vaping habits and product sources; tested products analyzed for ingredients.
Main Results:
- The study included 160 patients (62% male, median age 27). 46% required intensive care, and 29% needed mechanical ventilation; 4 deaths occurred.
- Of interviewed patients, 83% vaped THC products, 43% vaped CBD products, and 47% vaped nicotine products.
- Vitamin E acetate was found in 84% of tested THC-containing products obtained from informal sources.
Conclusions:
- Clinical outcomes and vaping behaviors in California patients mirror national trends, with a high prevalence of THC product use from informal sources.
- While Vitamin E acetate was frequently detected in THC products, other causes for EVALI may exist.
- Public health officials advise against using any vaping products, especially THC products from informal sources.
More Related Videos
09:30A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
Published on: January 18, 2018
8.7K
10:44Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
11.9K
Related Concept Videos
01:29Stimulants
770
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
770
01:17Pulmonary Cycle: Exhalation
2.8K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
2.8K
01:22Chronic Obstructive Pulmonary Disease
2.1K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.1K
01:20COPD: Pathogenesis and Clinical Features
1.7K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.7K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
3.4K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.4K
01:21Acute Respiratory Failure-II
928
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
928