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Updated: Dec 26, 2025

Bridging the Bio-Electronic Interface with Biofabrication
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Nanobiohybrid Material-Based Bioelectronic Devices.

Jinho Yoon1, Minkyu Shin1, Joungpyo Lim1

  • 1Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-Ro, Mapo-Gu, Seoul, 04107, Republic of Korea.

Biotechnology Journal
|March 7, 2020
PubMed
Summary

Nanobiohybrid materials combine biomolecules with nanomaterials to overcome limitations and enhance biochip functionality. This review explores their application in advanced bioelectronic devices.

Keywords:
biocomputingbioelectronic devicesbioelectronic sensing platformbiologic gatebioprocessornanobiohybrid material

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Area of Science:

  • Bioelectronics
  • Materials Science
  • Biotechnology

Background:

  • Biomolecules like proteins and nucleic acids are crucial for biochips but face limitations such as instability.
  • Functional nanomaterials offer potential to enhance and extend biomolecule capabilities on biochips.

Purpose of the Study:

  • To review recent advancements in bioelectronic devices utilizing nanobiohybrid materials.
  • To explore the potential of nanobiohybrid materials in creating next-generation multifunctional bioelectronic devices.

Main Methods:

  • Review of recently published research on nanobiohybrid materials for bioelectronics.
  • Analysis of the integration of functional nanomaterials with biomolecules.

Main Results:

  • Nanobiohybrid materials show significant potential for enhancing biomolecule function in bioelectronics.
  • Applications include sensitive electrochemical biosensors, logic gates, and biocomputing systems.

Conclusions:

  • Nanobiohybrid materials are key to overcoming biomolecule limitations in biochip development.
  • This review highlights innovative directions for future multifunctional bioelectronic devices.