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Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
Exploring the complex inter-relations between internalising symptoms, executive functioning and alcohol use in young
Briana Lees1, Lexine A Stapinski1, Katrina Prior1
1The Matilda Centre for Research in Mental Health and Substance Use, University of Sydney, Sydney, Australia.
Young adults with internalizing symptoms and executive functioning deficits show increased risk for alcohol use disorder. These factors, along with coping motives, predict hazardous drinking behaviors.
Area of Science:
- Psychology
- Neuroscience
- Public Health
Background:
- Hazardous drinking is prevalent in young adulthood.
- Evidence is mixed regarding the link between internalizing symptoms, executive functioning deficits, and increased risk for alcohol use disorder (AUD).
Purpose of the Study:
- To investigate the interaction between internalizing symptoms and executive functioning deficits in relation to AUD symptoms in emerging adulthood.
- To examine the mediating roles of drinking motives and alcohol consumption in this relationship.
Main Methods:
- A sample of 155 Australian young adults (17-24 years) provided self-report data on internalizing symptoms and alcohol outcomes.
- Neuropsychological tests measured executive functioning in a subset of participants (n=104).
- Latent moderated and mediated structural equation models were used to analyze the data.
Main Results:
- A significant interaction was found: high internalizing symptoms combined with executive functioning deficits predicted stronger coping motives for drinking, higher alcohol consumption, and greater AUD symptoms.
- Coping motives and alcohol consumption mediated the association between the internalizing symptoms and executive functioning interaction and AUD symptoms.
Conclusions:
- Greater executive functioning resources are linked to reduced motivation for hazardous drinking as a coping mechanism.
- Interventions targeting executive functioning and internalizing symptoms may be beneficial for preventing and treating alcohol use disorder in young people.
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