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[Effect of nitrogen on avermectins biosynthesis and its fermentation optimization based on carbon-dioxide evolution

Yao Xu1, Tao Wu1, Meijin Guo1

  • 1State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|March 10, 2020
PubMed
Summary

This study optimized avermectin production by controlling nitrogen levels and yeast powder feeding in Streptomyces avermitilis fermentation. Results show enhanced B1a synthesis and a 26.9% increase in avermectin yield.

Keywords:
Streptomyces avermitilisavermectincarbon-dioxide evolution rate (CER)yeast powder

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