Related Experiment Video
Updated: Dec 26, 2025

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
Published on: September 10, 2018
[Systemic drug treatment during pregnancy]
Maximilian Riedel1, Bettina Kuschel2
1Frauenklinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Deutschland.
Treating pregnant women requires careful consideration due to limited information and patient anxiety. Balancing therapy benefits and risks with symptom control ensures a safe pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Clinical Pharmacology
Background:
- Managing medical conditions in pregnant patients presents significant clinical challenges.
- Limited study data and patient apprehension regarding systemic treatments complicate treatment decisions.
Purpose of the Study:
- To highlight the complexities in clinical decision-making for treating pregnant women.
- To emphasize the importance of risk-benefit assessment and interdisciplinary care.
Main Methods:
- Review of current clinical practices and information availability for drug treatment in pregnancy.
- Analysis of factors influencing therapeutic choices and patient safety.
Main Results:
- Despite challenges, effective therapies with established safety profiles exist for many conditions during pregnancy.
- Informed therapeutic choices, symptom management, and collaborative care are vital.
Conclusions:
- Careful evaluation of potential benefits versus risks is paramount for selecting medical treatments in pregnancy.
- Optimal outcomes depend on appropriate medical treatment, symptom control, and interdisciplinary collaboration for a safe pregnancy.
More Related Videos
08:08Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model
Published on: June 18, 2013
11:51Systemic and Local Drug Delivery for Treating Diseases of the Central Nervous System in Rodent Models
Published on: August 16, 2010
Related Concept Videos
Factors Affecting Drug Response: Overview
Teratogenicity
Physiological Barriers
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...
Drug Therapy
Antianxiety Medications
Drug Dosage Regimen: Overview
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Pharmacokinetics in Pediatric Patients: Drug Excretion