Primary mesenteric fibromatosis: A single Center experience
Annali Italiani Di Chirurgia
|March 15, 2020
Summary
Primary mesenteric fibromatosis, a rare intra-abdominal tumor, requires wide surgical resection due to its aggressive nature and high recurrence rate. This study highlights surgical approaches and outcomes for this condition.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Primary mesenteric fibromatosis is a rare, locally invasive, non-metastasizing intra-abdominal tumor.
- It is characterized by a very high rate of recurrence.
- Keywords: Desmoid tumor, Fibromatosis, Mesentery, Mesenteric tumor.
Purpose of the Study:
- To present the surgical approach, tumor characteristics, clinical presentation, and long-term follow-up results for primary mesenteric fibromatosis.
Main Methods:
- Retrospective analysis of data from 11 patients who underwent surgery for primary mesenteric fibromatosis between 2010 and 2019.
- Evaluation of surgical techniques, clinical presentation, and patient outcomes.
Main Results:
- 11 patients (6 female, 5 male; mean age 44.2 years) presented with varied symptoms including abdominal pain, distention, and bowel obstruction.
- Abdominal masses were detected in 45.5% of patients.
- After a mean follow-up of 43.4 months, only one patient (9.1%) experienced recurrence, requiring reoperation.
- Postoperative mortality was 9.1% due to anastomotic leakage and sepsis, and another 9.1% died from other causes.
Conclusions:
- Wide surgical resection is the primary treatment principle for mesenteric fibromatosis due to its clinical aggressiveness and high recurrence rate.
- The condition presents with diverse clinical manifestations, necessitating accurate diagnosis via radiological imaging and confirmation through immunohistochemistry.
- Despite its benign pathological nature, effective management requires a comprehensive surgical strategy and vigilant follow-up.
