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Updated: Dec 26, 2025
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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
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[Thyrotropin-secreting pituitary adenoma]
Gábor Sohár1, Andrea Györkös1, Tamás Dóczi2
1I. Belgyógyászati és Infektológiai Osztály,Zala Megyei Szent Rafael KórházZalaegerszeg, Zrínyi M. út 1., 8900.
Orvosi Hetilap
|March 17, 2020
Summary
Thyrotropin-secreting pituitary tumors, a rare cause of hyperthyroidism, are increasingly diagnosed. Surgical removal of these tumors effectively restores thyroid hormone balance.
Area of Science:
- Endocrinology
- Neurosurgery
- Oncology
Background:
- Thyrotropin-secreting pituitary tumors are rare, causing hyperthyroidism in less than 1% of pituitary adenomas.
- Increased diagnosis is linked to advanced ultrasensitive thyrotropin (TSH) assays.
- These tumors should be suspected with normal to high TSH levels alongside elevated free thyroid hormones.
Observation:
- A case of a middle-aged female patient with hyperthyroidism due to a TSH-secreting pituitary macroadenoma is presented.
- Initial treatment involved temporary thyrostatic medication.
- The patient underwent successful tumor resection via neurosurgery.
Findings:
- Neurosurgical removal of the pituitary macroadenoma effectively resolved hyperthyroidism, restoring euthyroidism.
- Postoperative pituitary function was preserved.
- No recurrence was observed during follow-up, indicating successful treatment.
Implications:
- This case highlights the importance of considering TSH-secreting adenomas in hyperthyroid patients.
- Successful surgical management can lead to long-term remission and preserved pituitary function.
- Differential diagnosis challenges associated with these rare tumors are discussed.
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