Lymphoma on the Nasal Dorsum: Report of a Rare Case

Lymphoma over the nasal dorsum has never been reported. Herein, we report the case of a 74-year-old man who presented with a rapid swelling on the nasal dorsum. A physical examination revealed a firm, immobile, non-tender mass. Computed tomography revealed a space-occupying lesion in the subdermal layer of the nasal dorsum that was most likely a fibroma. An excisional biopsy was performed. Surprisingly, histopathological and immunohistochemical analyses identified a diffuse large B-cell lymphoma. The patient underwent seven cycles of chemotherapy comprising of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone. He responded well to the regimen. No evidence of persistent or recurrent disease had been detected during the 9 months after his last chemotherapy session. Although never reported previously, lymphoma can mimic common midline nasal soft-tissue tumors and should be considered in the differential diagnosis.