Etomidate plus fentanyl for anesthesia in pediatric strabotomy.

Area of Science:

• Anesthesiology
• Pediatric Surgery

Background:

• Etomidate, an anesthetic, often requires adjuncts to mitigate side effects and enhance efficacy.
• Ketamine is a commonly used anesthetic adjunct.

Purpose of the Study:

• To compare the efficacy of etomidate combined with fentanyl versus etomidate combined with ketamine for pediatric strabotomy anesthesia.
• To test the hypothesis that fentanyl is a more effective adjunct than ketamine when used with etomidate.

Main Methods:

• A prospective randomized controlled clinical study involving 70 pediatric patients undergoing strabotomy.
• Patients received either etomidate plus ketamine (Group A) or etomidate plus fentanyl (Group B).
• Hemodynamic parameters (MAP, HR), Bispectral Index (BIS), anesthesia effect, and emergence agitation/pain were monitored.

Main Results:

• Group B (etomidate-fentanyl) demonstrated significantly lower Mean Arterial Pressure (MAP) and Heart Rate (HR) from T3 to T5 compared to Group A.
• Bispectral Index (BIS) was significantly decreased in Group B from T2 to T4.
• Group B exhibited better anesthesia effects and lower emergence agitation and pain scores post-procedure.

Conclusions:

• Etomidate combined with fentanyl is an effective anesthetic regimen for pediatric strabotomy.
• The etomidate-fentanyl combination shows improved efficacy and reduced emergence complications compared to etomidate-ketamine.