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Updated: Dec 25, 2025

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Anti-Nuclear Antibody Screening Using HEp-2 Cells
Published on: June 23, 2014
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Anti-nuclear antibody-negative immunoglobulin G4-associated autoimmune hepatitis mimicking lymphoproliferative
Min Kyu Kang1, Jung Gil Park1, Joon Hyuk Choi2
1Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
Yeungnam University Journal of Medicine
|March 25, 2020
Abstract:
Immunoglobulin G4 (IgG4)-associated autoimmune hepatitis (AIH) is a very rare subtype of autoimmune hepatitis and characterized by marked elevated serum IgG and hepatic infiltration of IgG4-expressing plasma cells. Pathologic confirmation of hepatic IgG4-expressing plasma cells is usually required for the final diagnosis of IgG4-associated AIH. Herein, we report the case of a 47-year-old female diagnosed with autoantibody-negative IgG4-associated AIH mimicking lymphoproliferative disorders.

