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Related Concept Videos

Insomnia01:27

Insomnia

188
Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
188
Management of Insomnia01:19

Management of Insomnia

342
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
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Sleep-Wake Cycles01:24

Sleep-Wake Cycles

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Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
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Understanding Sleep01:11

Understanding Sleep

806
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
806
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

304
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
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Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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Updated: Oct 20, 2025

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia
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Published on: May 30, 2025

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Understanding insomnia as systemic disease.

Seokho Yun1, Sohye Jo1

  • 1Department of Psychiatry, Yeungnam University Hospital, Daegu, Korea.

Yeungnam University Journal of Medicine
|September 13, 2021
PubMed
Summary
This summary is machine-generated.

Insomnia disrupts sleep and daytime function, increasing risks for mental and physical health conditions. Recognizing insomnia as a systemic disease can improve understanding and prevent further health impairments.

Keywords:
ComorbidityInsomniaNeurophysiologySleep

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Area of Science:

  • Neuroscience
  • Sleep Medicine
  • Systemic Physiology

Background:

  • Sleep is vital for maintaining bodily and mental homeostasis.
  • Insomnia, a sleep disorder, impairs sleep initiation and maintenance.
  • It negatively impacts daytime cognitive function and emotional regulation.

Purpose of the Study:

  • To highlight insomnia's role as a systemic disease.
  • To underscore the broad health implications beyond the nervous system.
  • To encourage better understanding and treatment of insomnia.

Main Methods:

  • Literature review on the systemic effects of insomnia.
  • Analysis of insomnia's impact on various physiological systems.
  • Examination of treatment-seeking behaviors and associated costs.

Main Results:

  • Insomnia elevates risks for neuropsychiatric disorders like depression, anxiety, and dementia.
  • It affects cardiovascular, endocrine, and immune systems, increasing risks for hypertension, diabetes, and infections.
  • Many patients do not seek treatment due to underestimation of insomnia's widespread effects.

Conclusions:

  • Insomnia is a systemic disease with far-reaching consequences.
  • Understanding its systemic nature is crucial for comprehensive management.
  • This perspective can prevent secondary health impairments and reduce healthcare costs.