Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tunable Patterning of DNA Origami on Surfaces Using Steric Brushes.

Angewandte Chemie (International ed. in English)·2026
Same author

Retina-targeted siRNA delivery <i>via</i> exosome-liposome hybrid vesicles for AMD treatment.

Biomaterials science·2026
Same author

Biomimetic Microenvironment Nanomodulators for Reactive Oxygen Species-Responsive T<sub>1</sub>-T<sub>2</sub> Dual-Modal Magnetic Resonance Imaging and Visualized Treatment of Atherosclerosis.

ACS nano·2026
Same author

High-power dual-channel chamber for high-frequency magnetic neuromodulation.

Journal of neural engineering·2026
Same author

Expanding DNA alphabet adds a previously unknown dimension to nanostructures.

Science advances·2026
Same author

Nanoliposomal Co-Delivery of AR-PROTAC and NFKBIZ siRNA for Synergistic Therapy of Androgenetic Alopecia.

ACS applied bio materials·2026
Same journal

Intrinsic Superconducting Gap in Bilayer KCa<sub>2</sub>Fe<sub>4</sub>As<sub>4</sub>F<sub>2</sub> and Decoupled Monolayer FeAs.

Nano letters·2026
Same journal

Programmable Hydrogen-Assisted Chemical Vapor Deposition Growth and Bipolar Transport in Two-Dimensional MoO<sub>2</sub> Nanoflakes.

Nano letters·2026
Same journal

A Curvature-Modulated Strategy for Single-Atom Catalysts toward Reciprocal Regulation in Li-S Batteries.

Nano letters·2026
Same journal

Vacuum Pyrolysis Engineered CoSb/C Scaffold for Sodium Metal Anodes with Sodiophilic and Superionic Interphase.

Nano letters·2026
Same journal

Hexagonal SiGe Quantum Dots in Nanowires.

Nano letters·2026
Same journal

Monolithic Axial InGaAs Quantum Dot Emitters in GaAs-Based Nanowires via Sb-Mediated Facet Engineering.

Nano letters·2026
See all related articles

Related Experiment Video

Updated: Dec 25, 2025

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
09:17

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

9.1K

Programmable Assembly of Iron Oxide Nanoparticles Using DNA Origami.

Travis A Meyer1, Chuan Zhang2, Gang Bao3

  • 1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30322, United States.

Nano Letters
|March 27, 2020
PubMed
Summary
This summary is machine-generated.

DNA origami precisely controls magnetic iron oxide nanoparticle (IONP) assembly for enhanced biomedical applications. This method tunes IONP cluster functionality, improving MRI contrast and enabling dynamic biosensing capabilities.

Keywords:
DNA OrigamiIron Oxide NanoparticlesMagnetic Resonance Imaging ContrastSelf-Assembly

More Related Videos

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

15.0K
DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

12.0K

Related Experiment Videos

Last Updated: Dec 25, 2025

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
09:17

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

9.1K
Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

15.0K
DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

12.0K

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Materials Science

Background:

  • Magnetic iron oxide nanoparticles (IONPs) are valuable for biomedical uses.
  • Assembling IONPs into superstructures modifies their properties, including MRI contrast and hyperthermia efficiency.
  • Current IONP assembly methods often result in heterogeneous structures.

Purpose of the Study:

  • To develop a method for precise control over IONP assembly using DNA origami.
  • To investigate how controlled IONP clustering affects their functionality, particularly MRI contrast generation.
  • To demonstrate the dynamic regulation of these nanoparticle properties for potential biosensing applications.

Main Methods:

  • Utilized DNA origami to dictate the number and spatial arrangement of IONPs.
  • Fabricated precisely controlled IONP clusters.
  • Evaluated the MRI contrast generation efficiency of the assembled IONP structures.
  • Demonstrated dynamic property modulation of the IONP assemblies.

Main Results:

  • Achieved precise control over IONP number and positioning via DNA origami.
  • Demonstrated tunable MRI contrast enhancement by altering IONP number and spacing.
  • Showcased dynamic regulation of nanoparticle properties, indicating potential for responsive applications.

Conclusions:

  • DNA origami offers a robust platform for engineering IONP superstructures with tailored properties.
  • This precise assembly control enables optimization of IONP functionality for biomedical applications like improved MRI contrast.
  • The dynamic controllability of these nanostructures opens avenues for advanced biosensing technologies.