Related Experiment Video
Updated: Dec 25, 2025

Postoperative Ileus Murine Model
Published on: July 12, 2024
Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery
Nobuaki Hoshino1, Toshihiko Takada2, Koya Hida1
1Kyoto University Hospital, Department of Surgery, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, Japan, 606-8507.
This Cochrane Review was withdrawn due to a serious breach of conflict of interest policies. Funding Arbiters determined the review violated established ethical guidelines, leading to its retraction.
Area of Science:
- Systematic Reviews
- Evidence-Based Medicine
- Research Integrity
Background:
- Cochrane Reviews are high-quality systematic reviews.
- Maintaining research integrity and managing conflicts of interest are crucial in evidence synthesis.
Purpose of the Study:
- To report the withdrawal of a Cochrane Review.
- To explain the reason for withdrawal, citing a breach of conflict of interest policy.
Main Methods:
- A ruling by Cochrane's Funding Arbiters was the basis for the withdrawal.
- The ruling identified a serious breach of Cochrane's conflict of interest policy.
Main Results:
- The Cochrane Review in question has been officially withdrawn.
- A formal investigation confirmed a serious violation of conflict of interest regulations.
Conclusions:
- Serious breaches of conflict of interest policies necessitate the withdrawal of Cochrane Reviews.
- Upholding ethical standards and transparency is paramount in systematic reviews.
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