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Related Concept Videos

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Red algae, also known as rhodophytes, are primarily found in marine environments, though some species inhabit freshwater and terrestrial ecosystems. These organisms exist in both unicellular and multicellular forms, with some multicellular varieties reaching macroscopic sizes.As phototrophic organisms, red algae contain chlorophyll a; however, their chloroplasts lack chlorophyll b. Instead, they possess phycobiliproteins, which serve as major light-harvesting pigments, similar to those found in...
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Lectins from red algae and their biomedical potential.

Ram Sarup Singh1, Amandeep Kaur Walia1

  • 1Carbohydrate and Protein Biotechnology Laboratory, Department of Biotechnology, Punjabi University, Patiala, Punjab 147 002 India.

Journal of Applied Phycology
|March 28, 2020
PubMed
Summary
This summary is machine-generated.

Red algae lectins, proteins binding carbohydrates, show promise for antiviral therapies. Their specific interactions with glycans are key to developing new treatments for viral diseases.

Keywords:
Anti-viralCarbohydrate specificityHaemagglutinationLectinsRhodophyceae

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Area of Science:

  • Biochemistry
  • Marine Biology
  • Immunology

Background:

  • Lectins are carbohydrate-binding proteins of non-immune origin.
  • Red algae are a rich source of diverse lectins with specificities for complex carbohydrates.
  • These lectins mediate biochemical responses and have biomedical applications.

Purpose of the Study:

  • To review red algae lectins, their carbohydrate specificity, and characteristics.
  • To explore the anti-viral potential of red algae lectins against enveloped viruses.
  • To summarize other reported biomedical activities of these lectins.

Main Methods:

  • Literature review of studies on red algae lectins.
  • Analysis of carbohydrate-binding specificities.
  • Compilation of data on anti-viral and other biomedical activities.

Main Results:

  • Red algae lectins exhibit specificity towards complex glycoproteins and high-mannose N-glycans.
  • These lectins show potential anti-viral activity against HIV, influenza, coronavirus, and herpes simplex virus.
  • Other activities include anti-cancer, anti-microbial, anti-inflammatory, and anti-nociceptive effects.

Conclusions:

  • Red algae lectins are valuable tools in biomedical research due to their glycan recognition properties.
  • Their anti-viral and other biomedical activities warrant further investigation for therapeutic development.