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Updated: Dec 25, 2025
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A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues
Published on: December 5, 2016
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A fluorescent nanobiosensor for the facile analysis of m6A RNA demethylase activity
Seo-Hee Yim1, Hyung Jin Cha, Se-Jin Park
1Department of Chemistry, Seoul National University, Seoul 08826, Republic of Korea. dalheemin@snu.ac.kr.
Chemical Communications (Cambridge, England)
|March 28, 2020
Abstract:
RNA demethylase has recently been known to be associated with cancer development but its selective inhibitors as anti-cancer agents have rarely been investigated to date. Herein, we have developed a fluorescent nanobiosensor which enables efficient quantitative analysis of RNA demethylase ALKBH5 activity and shows a high potential for robust inhibitor screening.
