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Updated: Dec 25, 2025

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
Published on: April 28, 2023
[Obesity : eat less and move more ? Not so easy]
Jorge C Correia1,2, Florence Somers1, Alain Golay1
1Unité d'éducation thérapeutique du patient, Service d'endocrinologie, diabétologie, nutrition et d'éducation thérapeutique du patient, Centre collaborateur de l'OMS, Département de médecine, HUG, 1211 Genève 14.
Abstract:
Obesity is a chronic disease that requires a complex treatment. Establishing a balanced diet and regular physical activity is not always simple, especially in the long term. There are multiple factors (biological and psychological) favoring weight gain, often limiting the effectiveness of lifestyle approaches. Pharmacology offers us another therapeutic option with new molecules effective for weight loss. Bariatric surgery is also effective, but it is not without risks, especially if the patients have not been adequately prepared for this procedure. Furthermore, these approaches should always be proposed as complementary to lifestyle changes. This article summarizes the different treatments for obesity and highlights the importance of a multidisciplinary management and proper patient education.
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