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[Burden of comorbidities in heart failure patients hospitalized at the Abidjan Heart Institute]
K A Adoubi1, E Soya2, K D Bamba2
1Institut de cardiologie d'Abidjan, Abidjan, Cote d'Ivoire; Université de Bouaké, Bouaké, Cote d'Ivoire.
Insights
Comorbidities are frequent in heart failure patients, with hypertension and anemia being most common. These conditions significantly worsen prognosis and increase mortality risk in heart failure management.
Area of Science:
- Cardiology
- Internal Medicine
- Public Health
Background:
- Heart failure is a complex condition often accompanied by multiple comorbidities.
- Understanding the impact of these comorbidities is crucial for effective patient management and prognosis.
- Previous studies have highlighted the prevalence of comorbidities, but their specific impact on heart failure prognosis requires further investigation.
Purpose of the Study:
- To assess the prevalence and impact of comorbidities in hospitalized heart failure patients.
- To analyze the relationship between comorbidities, heart failure etiologies, and patient outcomes.
- To determine the prognostic significance of individual and multiple comorbidities in heart failure.
Main Methods:
- A prospective cohort study involving 302 adult heart failure patients admitted to the Cardiology Institute of Abidjan.
- Data collection included patient demographics, comorbidities, heart failure etiology, and follow-up for 12 months.
- Statistical analyses, including univariate and multivariate analyses (Cox model, Kaplan-Meier curves), were used to evaluate the impact of comorbidities on mortality.
Main Results:
- The most common comorbidities were high blood pressure (48%), anemia (43.7%), and kidney dysfunction (41.3%).
- Patients had an average of 3.4 comorbidities, with prevalence increasing with age.
- Hepatic dysfunction and a high Charlson index score were identified as significant risk factors for mortality.
Conclusions:
- Comorbidities are highly prevalent in heart failure patients.
- The presence and number of comorbidities significantly impact the prognosis of heart failure.
- Identifying and managing comorbidities is essential for improving outcomes in heart failure patients.
Objective:
The aim of our work was to appreciate the importance of comorbidities of heart failure individually and globally in patients hospitalized at the Cardiology Institute of Abidjan.
Patients And Methods:
This was a prospective cohort study of adult heart failure patients hospitalized from January to December 2015, and followed up over 12 months. Co-morbidities were analysed through their prevalence, their relationship with the etiologies, and their impact on the prognosis.
Results:
Three hundred and two patients (mean age: 55.5±16.9 years, 61.6 % male) were recruited. High blood pressure, anaemia and kidney dysfunction were the most common co-morbidities (48 %, 43.7 % and 41.3 % respectively). There was an average of 3.4±1.8 comorbidities per patient with an increase in the number of comorbidities with age (P<0.05) and a more frequent association with hypertensive and ischemic heart disease (P<0.001). During the one-year follow-up, 96 patients died. Apart from hepatic dysfunction (RR=1.97, 95 % CI [1,19-3.25], P=0.008, a high score of Charlson index appeared as a risk factor of death as much in univariate analysis (RR=4.15 95 % CI [2.32-7.41], P<0.001), as in multivariate analysis according to the Cox model (RR=2.48. 95 % CI [1.08-5.09], P=0.03) confirmed by Kaplan Meier curves (P<0.001).
Conclusion:
Comorbidities are common in our heart failure patients and significantly affect their prognosis.
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